Wound Bed Preparation
    Application Guidelines
    Estimating the Number and Size of Sheets
    Product Preparation
    Meshing and Handling
    Placement, Shaping and Cutting
    Stapling and Suturing
  Post-Op Care

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  • Fixation and compression are of significant importance. Elastic bandages, padded "tie-over" dressings, vacuum devices, splints and other methods, depending on circumstances, should be used to ensure the material adheres to the wound without shear, and that hematomas and seromas do not accumulate.
  • Inspect for hematoma and seroma formation upon dressing changes
  • Elastic net dressing can be attached by staples or other suitable methods. It will be left in
    place until the silicone is removed and offers the following advantages:

        - Helps prevent dislodgement

        - Keep INTEGRA™ Bilayer Matrix Wound Dressing in intimate contact with the wound bed

        - Easy to see through for observing Neodermis

  • When applied correctly, the expanded interstices will be open about 1-2 cm and the silicone
    will have slight indentations from the elastic net dressing
  • Apply non-adherent absorbent dressings as the inner dressing layer
  • Use topical antimicrobials such as silver impregnated dressings to help maintain a bacterial
    barrier over INTEGRA™ Bilayer Matrix Wound Dressing

Outer Dressings

Outer Dressings

  • Apply outer absorbent dressings
  • Use anti-shear dressings
  • Use bolsters where appropriate

       - Keep INTEGRA™ Bilayer Matrix Wound Dressing in intimate contact with the wound bed

       - Protect INTEGRA™ Bilayer Matrix Wound Dressing from shearing and detachment

  • Use bandages to apply slight pressure over outer dressings
  • Immobilize joints and limbs (e.g., by splinting) to prevent dislodgement


Do not let Dakins Solution, petroleum-based products, e.g., Xeroform, or enzymatic debridement agents, (e.g., Collagenase), come in contact with the INTEGRA™ Bilayer Matrix Wound Dressing application sites.

Use splints or bolsters, per unit protocols, during first 5-7 days. Splints should be applied and should stay on at all times (except when performing wound care).

The VAC (Vacuum Assisted Closure)* may be used over unmeshed or meshed INTEGRA™ Bilayer Matrix Wound Dressing sites, in particular, as a bolster dressing for difficult anatomical sites or wound beds, such as the axilla.

*VAC is a registered trademark of Kinetic Concepts, Inc. (KCI)

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