A prepared wound bed must be free
from contamination and infection. All necrotic and devitalized
tissue must be removed. Pre-Operative routines should
follow normal surgical center protocols. This may include
the use of systematic broad spectrum antibiotics. If
wound infection is detected, treat topically and/or
systemically according to unit protocols.
Achieve an adequate vascular supply
prior to the application of INTEGRA Matrix Wound Dressing. Punctate,
uniform capillary bleeding indicates adequate removal
of the affected tissue. Signs of a viable wound bed
include: white dermis, pure yellow fat and glistening
The wound bed must be dry with no
signs of bleeding. Meticulous hemostasis needs to be
achieved to prevent hematomas or excessive fluid accumulation.
Epinephrine, pinpoint electrocaudary, thrombin spray,
thrombin-soaked gauze or other topical hemostats should
be used. Avoid broad area cauterization which can lead
to devitalized tissue.
To ensure intimate contact with INTEGRA
Matrix Wound Dressing the wound bed must
be uniform and flat. Achieve level tissue planes and
when necessary, marsupialize edges to avoid large step-offs
between the wound bed and normal skin.
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