Most hematomas form within the first 24-48 hours. These can be treated by removing staples, lifting the matrix, evacuating the hematoma and addressing the cause of bleeding. This technique is also referred to
as "windowing." Late-forming hematomas are less common and typically form after 48 hours. These hematomas are incorporated into the surrounding Neodermis and/or matrix.

Consequently, they must be treated by removing the silicone over the affected area, excising the hematoma and either applying a new piece of INTEGRA Template or treating the area as an open wound until grafting.