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Introduction to INTEGRA Bilayer Matrix Wound
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Bilayer Matrix Wound Dressing is indicated
for the management of wounds including: partial
and full thickness wounds, pressure ulcers,
venous ulcers, diabetic ulcers, chronic and
vascular ulcers, surgical wounds (donor sites/grafts,
post-Moh's surgery, post-laser surgery, podiatric,
wound dehiscence), trauma wounds (abrasions,
lacerations, second-degree burns, and skin
tears) and draining wounds. This device is
intended for one-time use.
Bilayer Matrix Wound Dressing is an
advanced wound care device comprised of a
porous matrix of cross-linked bovine tendon
collagen and glycosaminoglycan and a semi-permeable
polysiloxane (silicone) layer. The semi-permeable
silicone membrane controls water vapor loss,
provides a flexible adherent covering for
the wound surface and adds increased tear
strength to the device. The collagen-glycosaminoglycan
biodegradable matrix provides a scaffold for
cellular invasion and capillary growth.
- The wound is surgically
debrided or excised to viable tissue and INTEGRA
Bilayer Matrix Wound Dressing is applied.
Over the next 2-4 weeks, the matrix is remodeled
as the patient's cells rebuild the damaged
site while simultaneously degrading the collagen-GAG
matrix. After the remodeled wound has developed,
the silicone layer is removed and complete
wound closure occurs as epidermal cells migrate
from the wound edges. For larger wounds, a
thin epidermal autograft 0.004-0.006 inches
(0.1016 - 0.1524 millimeters) may be applied.
As shown, wound closure is typically complete
in about 30 days.