Product Description and Benefits
  Indications for Use
  Product Makeup/Histology
  Clinical Sequence
    Ulceration to both feet and anterior ankles
    Trans-metatarsal amputation
    Traumatic degloving calcaneal fracture
    Stump Salvage
    Achilles Ulcer
    Exposed Bone
    Chronic Venous Ulceration
    Immunopathic Wound
    Exposed Joint
    Limb Salvage
    Leg Ulceration
    Arterial Disease
    Hypercoagulable Disorder
    Ankle Ulcer
    Ischemic Ulceration
    Forefoot Ulceration
    Heel Ulcer

Venous Stasis Ulceration
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A 62-year-old African American female with HIV and a chief complaint of a venous stasis ulceration was treated for approximately 6 years with compression dressings, various wound dressings, and skin grafts

Electrical/flame burn to neck

Following vein ablation surgery, the patient’s venous stasis ulcer was debrided down to the superficial fascia level

Fascial excision of chest

INTEGRA™ Bilayer Matrix Wound Dressing is cut to shape and stapled to the wound

INTEGRA® Dermal Regeneration Template

Following application of the graft, a silver impregnated dressing was used to cover the wound

Elastic net dressing

At two weeks, the dermal tissue is seen growing through
the pie crusted silicone layer

2 years post trauma

At three week post-op

Results of epidermal graft

After removal of the silicone, a split-thickness skin graft was utilized to cover the remodeled wound

2 years post trauma

At approximately 6 months post-op, the patient is fully recovered without ulceration

Results of epidermal graft

Cases Courtesy of:
Dave Granger D.P.M., Kevin Roberts D.P.M., Richard Jay D.P.M., Mark Mantell M.D., Paul Glat, M.D.
The Graduate Hospital Wound Care Center, Philadelphia, PA 19146

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